WebThe high dose NIH regimen can also be used at the supervising consultant’s discretion: Monthly IV CYC at 500-1000 mg/m2 body surface area for 6 months followed by 3 monthly IV CYC later for 2 years. Lower doses have been proven to be more effective and safer for lupus nephritis in Europe than high dose regimens. Maintenance therapy http://www.library.leicestershospitals.nhs.uk/PAGL/Shared%20Documents/Cyclophosphamide%20IV%20(Intravenous)%20UHL%20Rheumatology%20Guideline.pdf
Variability in experts
WebAug 1, 2013 · Complete remission was maintained in 39% of the patients in the rituximab group and in 33% of the patients in the comparison group. As compared with the results … WebAug 19, 2024 · given as a pulsed regimen. • IV CYC dose is typically calculated based on weight or body surface area and adjusted for renal function and age; given once every 2–4 weeks for up to 3–6 months. • For ANCA-associated vasculitis (AAV), the CYCLOPS regimen is used: IV CYC at dose of 15 mg/kg (reduced for age and renal function) each … bubbeltjesplastic action
European Vasculitis Study Group (EUVAS) AVERT project
WebThe high dose NIH regimen can also be used at the supervising consultant’s discretion: Monthly IV CYC at 500-1000 mg/m2 body surface area for 6 months followed by 3 … WebWith high-dose oral corticosteroids and pulsed intravenous cyclophosphamide, there was demonstrable clinical response. Ten courses of cyclophosphamide were completed over 6 months as per the CYCLOPS regimen,3 and mycophenolate mofetil (MMF) was commenced as maintenance therapy, while oral corticosteroids were tapered. WebRecommendations for the management of AAV. A collaboration between the European League Against Rheumatism (EULAR) and European Renal Association – … bubbe meaning